♦ Sputnik V is additionally acknowledged as Gam-COVID-Vac. It uses a heterogenous recombinant adenovirus approach. Meaning, Sputnik V is a two-vector vaccine. It makes use of Adeno Virus 26 in the first dose and Adeno Virus 5 in the 2nd dose. These Adeno Viruses are the carriers.
♦ A Conjugate Vaccine is a vaccine that makes use of a weak antigen with a robust antigen as a carrier. It is informally referred to as a provider vaccine. Sputnik V is a Conjugate Vaccine.
♦ Adenoviruses are common. They are ubiquitous (commonly determined everywhere) in an environment that is contaminated by means of human faeces or sewage. They purpose frequent cold and fever. This capability that the Adenovirus is many times observed in humans. This is one of the most important reasons why adeno virus-based COVID-19 vaccines are single-dose vaccines. However, Sputnik V used to be a double dose vaccine. This used to be performed to bolster the immune response, in contrast, to use the same vector twice.
♦ Sputnik V vaccine used to be sold at 10 USD in other markets. In India, it is dealing with difficulties to compete with AstraZeneca Vaccine, also referred to as COVISHIELD, which is sold at two USD per dose.
♦ The rate of COVISHIELD is low in India as it is manufactured regionally by means of the Serum Institute of India. On the other hand, Sputnik V is imported. It is marketed by Dr Reddy’s Laboratories.
♦ Now, to compete with COVISHILED and capture the market, the price has to be reduced, which is, fairly impossible as the vaccine is being imported. Thus, a single dose vaccine is being launched. India is planning to launch this single-dose vaccine.